Ubiquilin 1 antibody
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- Target See all Ubiquilin 1 (UBQLN1) Antibodies
- Ubiquilin 1 (UBQLN1)
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ubiquilin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- ubiquilin 1
- Isotype
- IgG
- Top Product
- Discover our top product UBQLN1 Primary Antibody
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- Application Notes
- WB: 1:200-1:1000, IF: 1:10-1:100, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- Ubiquilin 1 (UBQLN1)
- Alternative Name
- Ubiquilin 1 (UBQLN1 Products)
- Synonyms
- UBQLN1 antibody, DA41 antibody, DSK2 antibody, PLIC-1 antibody, UBQN antibody, XDRP1 antibody, 1110046H03Rik antibody, 1810030E05Rik antibody, AU019746 antibody, C77538 antibody, D13Ertd372e antibody, Da41 antibody, Dsk2 antibody, Plic-1 antibody, Plic1 antibody, Xdrp1 antibody, ubiquilin 1 antibody, UBQLN1 antibody, Ubqln1 antibody
- Background
- Synonyms:DA41, DSK2, FLJ90054, hPLIC 1, PLIC 1, PLIC1, ubiquilin 1, UBQLN1, XDRP1 Background:UBQLN1, also known as DSK2 or Ubiquilin 1, is an ubiquitin-like proteinis contains a?N-terminal?ubiquitin-like?domain?and a C-terminal ubiquitin-associated domain.?They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation.Ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with?Alzheimer's?and?Parkinson's?disease. Two transcript variants encoding different isoforms have been found for this gene. Higher levels of ubiquilin-1 in the brain decreased malformation of the APP molecule which plays a key role in triggering Alzheimers disease.Conversely, lower levels of ubiquilin-1 in the brain were associated with increased malformation of APP?(PMID: 21852239). This antibody detects 70kD band of UBQLN1.
- Molecular Weight
- 71 kDa
- UniProt
- Q9UMX0
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