Recombinant IL-7 antibody (AA 27-177)
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- Target See all IL-7 (IL7) Antibodies
- IL-7 (IL7) (Interleukin 7 (IL7))
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- AA 27-177
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This IL-7 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor i³ chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa 27-177) corresponding to mature protein of human IL7(exact sequence is proprietary)
- Isotype
- IgG
- Top Product
- Discover our top product IL7 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Human thymus or tonsil tissue.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- IL-7 (IL7) (Interleukin 7 (IL7))
- Alternative Name
- IL7 (IL7 Products)
- Synonyms
- IL7 antibody, IL-7 antibody, A630026I06Rik antibody, Il-7 antibody, hlb368 antibody, interleukin 7 antibody, IL7 antibody, Il7 antibody
- Background
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IL 7, IL-7, Il7, Interleukin 7, Interleukin-7, LP-1, Lymphopoietin 1,Interleukin-7 (IL-7)
Cellular localisation: Secreted. - Molecular Weight
- 25kDa
- Gene ID
- 3574, 591873
- Pathways
- JAK-STAT Signaling
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