CD79b antibody (AA 29-159)
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- Target See all CD79b (CD79B) Antibodies
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
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Binding Specificity
- AA 29-159
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD79b antibody is un-conjugated
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Application
- ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
- Cross-Reactivity (Details)
- Human
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment of human CD79b protein (around aa 29-159) (exact sequence is proprietary)
- Isotype
- IgG1
- Top Product
- Discover our top product CD79B Primary Antibody
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- Application Notes
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- Alternative Name
- CD79B (CD79B Products)
- Synonyms
- B29 antibody, Ig-beta antibody, Igb antibody, Igbeta antibody, AGM6 antibody, IGB antibody, CD79B antigen antibody, CD79b molecule antibody, Cd79b antibody, CD79B antibody
- Background
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AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein,CD79b (B-Cell Marker)
Cellular localisation: Cell Surface - Molecular Weight
- 39kDa
- Gene ID
- 974, 89575
- UniProt
- P40259
- Pathways
- BCR Signaling
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