Recombinant PTGS1 antibody

Catalog No. ABIN7321571

Product Details anti-PTGS1 Antibody

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PTGS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human COX1

Clone: 6B6

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, FC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Alternative Name: PTGS1 (PTGS1 Products)

Synonyms: COX-1 antibody, cox-1 antibody, PTGS1 antibody, Ptgs1 antibody, COX1 antibody, Cox-1 antibody, Cox-3 antibody, PGHS-1 antibody, PHS 1 antibody, Pghs1 antibody, Cox1 antibody, Cox3 antibody, cox1 antibody, zCOX-1 antibody, COX3 antibody, PCOX1 antibody, PES-1 antibody, PGG/HS antibody, PGHS1 antibody, PHS1 antibody, PTGHS antibody, COX-3 antibody, prostaglandin-endoperoxide synthase 1 antibody, cyclooxygenase-1 antibody, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) antibody, prostaglandin-endoperoxide synthase 1 S homeolog antibody, PTGS1 antibody, cox-1 antibody, Ptgs1 antibody, ptgs1 antibody, ptgs1.S antibody

Background:

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Aliases: Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1), PTGS1, COX1

UniProt: P23219