CHRNA4 antibody

Catalog No. ABIN7337147

Product Details anti-CHRNA4 Antibody

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human CHRNA4

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Alternative Name: CHRNA4 (CHRNA4 Products)

Synonyms: NACHRA4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACHR antibody, NACRA4 antibody, NARAC antibody, Acra-4 antibody, Acra4 antibody, ENFL1 antibody, neuronal acetylcholine receptor subunit alpha-4 antibody, neuronal acetylcholine receptor subunit alpha-4-like antibody, cholinergic receptor nicotinic alpha 4 subunit antibody, cholinergic receptor, nicotinic, alpha 4b antibody, cholinergic receptor, nicotinic, alpha polypeptide 4 antibody, CpipJ_CPIJ002434 antibody, LOC100368057 antibody, CHRNA4 antibody, chrna4b antibody, Chrna4 antibody

Background:

Background: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1.

Aliases: A4 nicotinic receptor antibody, Acetylcholine receptor alpha 4 neural antibody, Acetylcholine receptor neuronal nicotinic alpha 4 subunit antibody, ACH 4 antibody, ACH4 antibody, ACHA4_HUMAN antibody, AChR antibody, Acra 4 antibody, Acra4 antibody, Alpha4 nAChR antibody, BFNC antibody, Cholinergic receptor nicotinic alpha 4 antibody, Cholinergic receptor nicotinic alpha polypeptide 4 antibody, CHRNA 4 antibody, CHRNA4 antibody, EBN 1 antibody, EBN antibody, EBN1 antibody, NACHR antibody, NACRA 4 antibody, NACRA4 antibody, Neuronal acetylcholine receptor subunit alpha-4 antibody, Neuronal nicotinic acetylcholine receptor alpha 4 subunit antibody

UniProt: P43681

Pathways: Synaptic Membrane