TLR2 antibody

Catalog No. ABIN7336296

Product Details anti-TLR2 Antibody

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human TLR2

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Alternative Name: TLR2 (TLR2 Products)

Synonyms: CD282 antibody, TIL4 antibody, Ly105 antibody, toll like receptor 2 antibody, toll-like receptor 2 antibody, TLR2 antibody, Tlr2 antibody, tlr2 antibody

Background:

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Aliases: CD282 antibody, CD282 antigen antibody, TIL 4 antibody, TIL4 antibody, TLR 2 antibody, TLR2 antibody, TLR2_HUMAN antibody, Toll like receptor 2 antibody, Toll like receptor 2 precursor antibody, Toll-like receptor 2 antibody, Toll/interleukin 1 receptor like 4 antibody, Toll/interleukin 1 receptor like protein 4 antibody, Toll/interleukin receptor like protein 4 antibody, Toll/interleukin-1 receptor-like protein 4 antibody

UniProt: O60603

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades