Cyclin C antibody (pSer275)

Catalog No. ABIN7138527

Product Details anti-Cyclin C Antibody

Target: Cyclin C (CCNC)

Binding Specificity: pSer275

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 275(N-G-S(p)-A-N) derived from Human Cyclin C.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cyclin C

Target: Cyclin C (CCNC)

Alternative Name: CCNC (CCNC Products)

Synonyms: CG1C_DROME antibody, CG7281 antibody, CYCC antibody, Cln3 antibody, Cyc-C antibody, DmcycC antibody, Dmel\\CG7281 antibody, SRB11 antibody, cycC antibody, cyclinC antibody, dTRAP33 antibody, fj11d06 antibody, wu:fj11d06 antibody, zgc:73078 antibody, Cyclin-C antibody, CycC antibody, AI451004 antibody, AU020987 antibody, CG1C antibody, Cyclin C antibody, cyclin C antibody, cyclin C L homeolog antibody, cyclin-C antibody, CycC antibody, ccnc antibody, CCNC antibody, Ccnc antibody, ccnc.L antibody, LOC5577815 antibody

Background:

Background:

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

Lew D.J., Cell 66:1197-1206(1991).
Li H., Genomics 32:253-259(1996).
Mungall A.J., Nature 425:805-811(2003).

Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody

UniProt: P24863

Pathways: Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha