MAP2K4 antibody (pThr261)

Catalog No. ABIN7138894

Product Details anti-MAP2K4 Antibody

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Binding Specificity: pThr261

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine261 (A-K-T(p)-RD) derived from Human SEK1/MKK4.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAP2K4

Target: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Alternative Name: MAP2K4 (MAP2K4 Products)

Synonyms: JNKK antibody, JNKK1 antibody, MAPKK4 antibody, MEK4 antibody, MKK4 antibody, PRKMK4 antibody, SAPKK-1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Sek1 antibody, Serk1 antibody, MKK4A-l antibody, map2k4 antibody, zgc:136500 antibody, jnkk antibody, mek4 antibody, mkk4 antibody, sek1 antibody, jnkk1 antibody, serk1 antibody, xmek2 antibody, mapkk4 antibody, prkmk4 antibody, 142758_at antibody, CG9738 antibody, CT27508 antibody, D-MKK4 antibody, DMKK4 antibody, Dmel\\CG9738 antibody, JNKK2 antibody, Mpk4 antibody, SEK1/MKK4 antibody, dMKK4 antibody, dMkk4 antibody, hep antibody, ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 antibody, ATMEK4 antibody, ATMKK4 antibody, F19C24.26 antibody, F19C24_26 antibody, MAP KINASE KINASE 4 antibody, mitogen-activated protein kinase kinase 4 antibody, MKK4B antibody, zgc:194486 antibody, mitogen-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4a antibody, MAP kinase kinase 4 antibody, mitogen activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 4b antibody, MAP2K4 antibody, Map2k4 antibody, map2k4a antibody, map2k4 antibody, Mkk4 antibody, MKK4 antibody, map2k4b antibody

Background:

Background: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

Wang W, et al. (2002) Mol Cell Biol, 22(10): 3389-403.
Leung IW, et al. (2001) J Biol Chem, 276(3): 1961-7.

Aliases: c Jun N terminal kinase kinase 1 antibody, C-JUN N-terminal kinase kinase 1 antibody, Dual specificity mitogen activated protein kinase kinase 4 antibody, Dual specificity mitogen-activated protein kinase kinase 4 antibody, JNK Activated Kinase 1 antibody, JNK activating kinase 1 antibody, JNK-activating kinase 1 antibody, JNKK antibody, JNKK1 antibody, MAP kinase kinase 4 antibody, Map2k4 antibody, MAPK ERK kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, MAPKK4 antibody, MEK 4 antibody, MEK4 antibody, Mitogen activated protein kinase kinase 4 antibody, MKK 4 antibody, MKK4 antibody, MP2K4_HUMAN antibody, PRKMK4 antibody, SAPK ERK kinase 1 antibody, SAPK/ERK kinase 1 antibody, SAPKK 1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Stress activated protein kinase kinase 1 antibody

UniProt: P45985

Pathways: MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling