TCF7L1 antibody (AA 80-99) (Biotin)

Catalog No. ABIN7140178

Product Details anti-TCF7L1 Antibody (Biotin)

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Binding Specificity: AA 80-99

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF7L1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Transcription factor 7-like 1 protein (80-99AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TCF7L1

Target: TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))

Alternative Name: TCF7L1 (TCF7L1 Products)

Synonyms: TCF-3 antibody, TCF3 antibody, Tcf-3 antibody, Tcf3 antibody, bHLHb21 antibody, tcf3c antibody, tcf3d antibody, xtcf3 antibody, XTCF-3 antibody, tcf7l1 antibody, tcf3b antibody, TCF-3-A antibody, tcf-3 antibody, tcf3 antibody, tcf3a antibody, zTcf-3 antibody, transcription factor 7 like 1 antibody, transcription factor 7 like 1 (T cell specific, HMG box) antibody, transcription factor 7 like 1 L homeolog antibody, transcription factor 7 like 1 S homeolog antibody, transcription factor 7 like 1b antibody, transcription factor 7 like 1a antibody, TCF7L1 antibody, Tcf7l1 antibody, tcf7l1.L antibody, tcf7l1.S antibody, tcf7l1b antibody, tcf7l1a antibody

Background:

Background: Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Aliases: bHLHb21 antibody, HMG box transcription factor 3 antibody, HMG box transcription factor antibody, OTTMUSP00000023419 antibody, T cell factor 3 antibody, TCF 3 antibody, TCF-3 antibody, TCF3 antibody, Tcf7l1 antibody, TF7L1_HUMAN antibody, Transcription factor 7 like 1 (T-cell specific, HMG-box) antibody, Transcription factor 7 like 1 antibody, Transcription factor 7-like 1 antibody

UniProt: Q9HCS4

Pathways: WNT Signaling, Stem Cell Maintenance