HTR2A antibody (AA 385-471) (Biotin)

Catalog No. ABIN7142623

This anti-HTR2A antibody is a Rabbit Polyclonal antibody detecting HTR2A in ELISA. Suitable for Human.

Quick Overview for HTR2A antibody (AA 385-471) (Biotin) (ABIN7142623)

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR2A antibody is conjugated to Biotin

Application: ELISA

Product Details anti-HTR2A Antibody (Biotin)

Binding Specificity: AA 385-471

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human 5-hydroxytryptamine receptor 2A protein (385-471AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HTR2A

Target: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Alternative Name: HTR2A

Background:

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

Aliases: 5 HT 2 antibody, 5 HT 2A antibody, 5 HT2 receptor antibody, 5 HT2A antibody, 5 hydroxytryptamine receptor 2A antibody, 5-HT-2 antibody, 5-HT-2A antibody, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled antibody, 5-hydroxytryptamine 2A receptor antibody, 5-hydroxytryptamine receptor 2A antibody, 5HT2A_HUMAN antibody, HTR 2 antibody, HTR 2A antibody, HTR2 antibody, HTR2, formerly antibody, HTR2A antibody, serotonin 5-HT-2 receptor, formerly antibody, serotonin 5-HT-2A receptor antibody, Serotonin receptor 2A antibody

UniProt: P28223

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process