NDST1 antibody (AA 40-556)

Catalog No. ABIN7347247

Product Details anti-NDST1 Antibody

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Binding Specificity: AA 40-556

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDST1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 protein (40-556AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NDST1

Target: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Alternative Name: NDST1 (NDST1 Products)

Synonyms: HSST antibody, NST1 antibody, 1200015G06Rik antibody, Hsst antibody, NDST-1 antibody, fj47c03 antibody, ndst1 antibody, wu:fj47c03 antibody, NDST1 antibody, N-deacetylase and N-sulfotransferase 1 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog antibody, NDST1 antibody, Ndst1 antibody, ndst1b antibody, ndst1 antibody, ndst1.S antibody

Background:

Background: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Aliases: NDST1 antibody, HSST antibody, HSST1 antibody, Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 antibody, EC 2.8.2.8 antibody, Glucosaminyl N-deacetylase/N-sulfotransferase 1 antibody, NDST-1 antibody, N-heparan sulfate sulfotransferase 1 antibody, N-HSST 1 antibody, [Heparan sulfate]-glucosamine N-sulfotransferase 1 antibody, HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 antibody, EC 3.-.-.-), Heparan sulfate N-sulfotransferase 1 antibody, EC 2.8.2.-)] antibody

UniProt: P52848

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process