RLTPR antibody (AA 1136-1290)

Catalog No. ABIN7146660

Product Details anti-RLTPR Antibody

Target: RLTPR (RGD Motif, Leucine Rich Repeats, Tropomodulin Domain and Proline-Rich Containing (RLTPR))

Binding Specificity: AA 1136-1290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RLTPR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Capping protein, Arp2/3 and myosin-I linker protein 2 protein (1136-1290AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RLTPR

Target: RLTPR (RGD Motif, Leucine Rich Repeats, Tropomodulin Domain and Proline-Rich Containing (RLTPR))

Alternative Name: CARMIL2 (RLTPR Products)

Synonyms: CG1399-PB antibody, D130029J02Rik antibody, Gm585 antibody, CARMIL2 antibody, CARMIL2b antibody, LRRC16C antibody, capping protein regulator and myosin 1 linker 2 antibody, F-actin-uncapping protein RLTPR antibody, RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing antibody, Carmil2 antibody, CARMIL2 antibody, LOC100021093 antibody, LOC100091608 antibody, RLTPR antibody

Background:

Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization (PubMed:26466680). Plays a role in cell protrusion formations, involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations (PubMed:19846667, PubMed:26578515, PubMed:26466680). Involved as well in cell migration and invadopodia formation during wound healing (PubMed:19846667, PubMed:26578515, PubMed:26466680).

Aliases: CARMIL2 antibody, CARMIL2b antibody, Leucine rich repeat containing 16C antibody, leucine-rich repeat antibody, Leucine-rich repeat-containing protein 16C antibody, LR16C_HUMAN antibody, LRRC16C antibody, RGD antibody, RGD leucine rich repeat tropomodulin and proline rich containing protein antibody, RGD motif leucine rich repeats tropomodulin domain and proline rich containing antibody, Rltpr antibody, tropomodulin and proline-rich-containing protein antibody

UniProt: Q6F5E8