IGF2R antibody (AA 2328-2491)

Catalog No. ABIN7147047

Product Details anti-IGF2R Antibody

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Binding Specificity: AA 2328-2491

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2R antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cation-independent mannose-6-phosphate receptor protein (2328-2491AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IGF2R

Target: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Alternative Name: IGF2R (IGF2R Products)

Synonyms: CD222 antibody, CIMPR antibody, M6P-R antibody, MPR1 antibody, MPRI antibody, AI661837 antibody, CI-MPR antibody, M6P/IGF2R antibody, Mpr300 antibody, mpri antibody, cd222 antibody, cimpr antibody, m6p-r antibody, insulin like growth factor 2 receptor antibody, insulin-like growth factor 2 receptor antibody, IGF2R antibody, Igf2r antibody, igf2r antibody

Background:

Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Aliases: 300 kDa mannose 6 phosphate receptor antibody, 300 kDa mannose 6-phosphate receptor antibody, Cation independent mannose 6 phosphate receptor antibody, Cation-independent mannose-6-phosphate receptor antibody, CD222 antibody, CD222 antigen antibody, CI Man 6 P receptor antibody, CI Man-6-P receptor antibody, CI MPR antibody, CI-M6PR antibody, CI-MPR antibody, CIMPR antibody, IGF 2 receptor antibody, IGF 2R antibody, IGF II receptor antibody, IGF-II receptor antibody, IGF2 receptor antibody, Igf2r antibody, Insulin like growth factor 2 receptor antibody, Insulin like growth factor II receptor antibody, Insulin-like growth factor 2 receptor antibody, Insulin-like growth factor II receptor antibody, M6P R antibody, M6P/IGF2 receptor antibody, M6P/IGF2R antibody, M6PR antibody, mannose 6 phosphate receptor antibody, mannose 6 phosphate receptor, cation independent antibody, MPR 300 antibody, MPR300 antibody, MPRI antibody, MPRI_HUMAN antibody

UniProt: P11717