ATG4A antibody (AA 1-214) (HRP)

Catalog No. ABIN7357903

Product Details anti-ATG4A Antibody (HRP)

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Binding Specificity: AA 1-214

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cysteine protease ATG4A protein (1-214AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Alternative Name: ATG4A (ATG4A Products)

Synonyms: apg4a antibody, autl2 antibody, F6E13.27 antibody, APG4A antibody, zgc:111958 antibody, Aut2a antibody, AUTL2 antibody, AI627006 antibody, AV169859 antibody, Apg4a antibody, Atg4al antibody, Autl2 antibody, Atg4a antibody, autophagy related 4A cysteine peptidase L homeolog antibody, autophagy related 4A cysteine peptidase antibody, Peptidase family C54 protein antibody, ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody, autophagy related 4A, cysteine peptidase antibody, atg4a.L antibody, ATG4A antibody, AT2G44140 antibody, atg4a antibody, Atg4a antibody

Background:

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Aliases: AI627006 antibody, APG4 autophagy 4 homolog A antibody, Apg4a antibody, ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody, ATG4 autophagy related 4 homolog A antibody, ATG4A antibody, ATG4A_HUMAN antibody, Atg4al antibody, AUT like 2 cysteine endopeptidase antibody, AUT-like 2 cysteine endopeptidase antibody, Autl2 antibody, Autophagin 2 antibody, Autophagin-2 antibody, Autophagy related 4A cysteine peptidase antibody, Autophagy related cysteine endopeptidase 2 antibody, Autophagy related protein 4 homolog A antibody, Autophagy-related cysteine endopeptidase 2 antibody, Autophagy-related protein 4 homolog A antibody, AV169859 antibody, Cysteine protease ATG4A antibody, hAPG4A antibody, MGC107179 antibody

UniProt: Q8WYN0

Pathways: Autophagy