MLKL antibody (AA 1-471) (Biotin)

Catalog No. ABIN7358357

Product Details anti-MLKL Antibody (Biotin)

Target: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Binding Specificity: AA 1-471

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLKL antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mixed lineage kinase domain-like protein (1-471AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MLKL

Target: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Alternative Name: MLKL (MLKL Products)

Synonyms: MLKL antibody, 9130019I15Rik antibody, mixed lineage kinase domain like pseudokinase antibody, mixed lineage kinase domain-like antibody, MLKL antibody, mlkl antibody, Mlkl antibody

Background:

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Aliases: 9130019I15Rik antibody, FLJ34389 antibody, hMLKL antibody, Mixed lineage kinase domain like antibody, Mixed lineage kinase domain like protein antibody, Mixed lineage kinase domain like pseudokinase antibody, Mixed lineage kinase domain-like protein antibody, Mlkl antibody, MLKL_HUMAN antibody

UniProt: Q8NB16