CHRNA9 antibody (AA 26-240)

Catalog No. ABIN7161350

Product Details anti-CHRNA9 Antibody

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Binding Specificity: AA 26-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Neuronal acetylcholine receptor subunit alpha-9 protein (26-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRNA9

Target: CHRNA9 (Cholinergic Receptor, Nicotinic, alpha 9 (Neuronal) (CHRNA9))

Alternative Name: CHRNA9 (CHRNA9 Products)

Synonyms: HSA243342 antibody, NACHRA9 antibody, 2410015I05Rik antibody, Acra9 antibody, EG666827 antibody, Gm8311 antibody, cholinergic receptor nicotinic alpha 9 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 9 antibody, CHRNA9 antibody, Chrna9 antibody

Background:

Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840).

Aliases: CHRNA9 antibody, NACHRA9Neuronal acetylcholine receptor subunit alpha-9 antibody, Nicotinic acetylcholine receptor subunit alpha-9 antibody, NACHR alpha-9 antibody

UniProt: Q9UGM1

Pathways: Sensory Perception of Sound