PHLDA3 antibody (AA 43-95) (FITC)
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- Target See all PHLDA3 Antibodies
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
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Binding Specificity
- AA 43-95
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHLDA3 antibody is conjugated to FITC
- Application
- Please inquire
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
- Isotype
- IgG
- Top Product
- Discover our top product PHLDA3 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
- Alternative Name
- PHLDA3 (PHLDA3 Products)
- Synonyms
- TIH1 antibody, Tih1 antibody, si:dz182n13.5 antibody, zgc:92333 antibody, pleckstrin homology like domain family A member 3 antibody, pleckstrin homology like domain, family A, member 3 antibody, pleckstrin homology-like domain, family A, member 3 antibody, PHLDA3 antibody, Phlda3 antibody, phlda3 antibody
- Background
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Background: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Aliases: PHLA3_HUMAN antibody, PHLDA 3 antibody, phlda3 antibody, Pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology like domain family A member 3 antibody, Pleckstrin homology-like domain family A member 3 antibody, TDAG51/Ipl homolog 1 antibody, TDAG51/Ipl homologue 1 antibody, TIH 1 antibody, TIH1 antibody
- UniProt
- Q9Y5J5
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