SCN8A antibody (AA 1350-1440)

Catalog No. ABIN7169927

This Rabbit Polyclonal antibody specifically detects SCN8A in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for SCN8A antibody (AA 1350-1440) (ABIN7169927)

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN8A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-SCN8A Antibody

Binding Specificity: AA 1350-1440

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Sodium channel protein type 8 subunit alpha protein (1350-1440AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Alternative Name: SCN8A

Background:

Background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Aliases: CerIII antibody, CIAT antibody, EIEE13 antibody, hNa6/Scn8a voltage gated sodium channel antibody, MED antibody, Motor endplate disease antibody, NaCh 6 antibody, NaCh6 antibody, Nav 1.6 antibody, Nbna1 antibody, peripheral nerve protein type 4 antibody, PN 4 antibody, PN4 antibody, SCN8A antibody, SCN8A_HUMAN antibody, Sodium channel protein type 8 alpha subunit antibody, Sodium channel protein type 8 subunit alpha antibody, Sodium channel protein type VIII alpha subunit antibody, Sodium channel protein type VIII subunit alpha antibody, Sodium channel voltage gated type VIII alpha antibody, Sodium channel voltage gated type VIII alpha polypeptide antibody, Sodium channel voltage gated type VIII alpha subunit antibody, Voltage gated sodium channel subunit alpha Nav1.6 antibody, Voltage-gated sodium channel subunit alpha Nav1.6 antibody

UniProt: Q9UQD0

Pathways: Sensory Perception of Sound