TSC22D3 antibody (AA 58-134) (FITC)
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- Target See all TSC22D3 Antibodies
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
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Binding Specificity
- AA 58-134
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TSC22D3 antibody is conjugated to FITC
- Application
- Please inquire
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human TSC22 domain family protein 3 protein (58-134AA)
- Isotype
- IgG
- Top Product
- Discover our top product TSC22D3 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- Alternative Name
- TSC22D3 (TSC22D3 Products)
- Synonyms
- dsipi antibody, MGC53285 antibody, zgc:65831 antibody, zgc:77028 antibody, TSC22D3 antibody, GILZ antibody, gilz antibody, tsc-22r antibody, DIP antibody, DSIPI antibody, TSC-22R antibody, hDIP antibody, Dsip1 antibody, Gilz antibody, Tilz3 antibody, Dsipi antibody, DSIP antibody, TSC22 domain family member 3 L homeolog antibody, TSC22 domain family, member 3 antibody, TSC22 domain family member 3 antibody, tsc22d3.L antibody, tsc22d3 antibody, TSC22D3 antibody, Tsc22d3 antibody
- Background
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Background: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.
Aliases: Delta sleep-inducing peptide immunoreactor antibody, DIP antibody, DSIP immunoreactive leucine zipper protein antibody, DSIP-immunoreactive peptide antibody, Dsip1 antibody, Dsipi antibody, GILZ antibody, Glucocorticoid-induced leucine zipper protein antibody, hDIP antibody, Protein DIP antibody, T22D3_HUMAN antibody, TSC-22-like protein antibody, TSC-22-related protein antibody, TSC-22R antibody, TSC22 domain family protein 3 antibody, TSC22 domain family, member 3 antibody, TSC22 related inducible leucine zipper 3 antibody, TSC22D3 antibody
- UniProt
- Q99576
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