WDFY2 antibody (AA 2-114)
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- Target See all WDFY2 (ZFYVE22) Antibodies
- WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))
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Binding Specificity
- AA 2-114
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WDFY2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human WD repeat and FYVE domain-containing protein 2 protein (2-114AA)
- Isotype
- IgG
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))
- Alternative Name
- WDFY2 (ZFYVE22 Products)
- Synonyms
- PROF antibody, RP11-147H23.1 antibody, WDF2 antibody, ZFYVE22 antibody, 5830485M08 antibody, B130024L21Rik antibody, ProF antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD repeat and FYVE domain containing 2 antibody, wdfy-2 antibody, WDFY2 antibody, Wdfy2 antibody
- Background
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Background: Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling, required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).
Aliases: PROF antibody, Propeller-FYVE protein antibody, RP11 147H23.1 antibody, WD repeat and FYVE domain containing 2 antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD40 and FYVE domain containing 2 antibody, WD40- and FYVE domain-containing protein 2 antibody, WDF2 antibody, Wdfy2 antibody, WDFY2_HUMAN antibody, ZFYVE22 antibody, Zinc finger FYVE domain-containing protein 22 antibody
- UniProt
- Q96P53
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