Complement Factor B antibody (AA 23-761) (HRP)

Catalog No. ABIN7372221

Product Details anti-Complement Factor B Antibody (HRP)

Target: Complement Factor B (CFB)

Binding Specificity: AA 23-761

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement Factor B antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Mouse Complement factor B protein (23-761AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Complement Factor B

Target: Complement Factor B (CFB)

Alternative Name: Cfb (CFB Products)

Synonyms: AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody

Background:

Background: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Aliases: Cfb antibody, Bf antibody, H2-BfComplement factor B antibody, EC 3.4.21.47 antibody, C3/C5 convertase) [Cleaved into: Complement factor B Ba fragment, Complement factor B Bb fragment] antibody

UniProt: P04186

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process