desert Hedgehog antibody

Catalog No. ABIN7341942

Product Details anti-desert Hedgehog Antibody

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This desert Hedgehog antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human DHH

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Alternative Name: DHH (DHH Products)

Synonyms: GDXYM antibody, HHG-3 antibody, SRXY7 antibody, C78960 antibody, Xchh antibody, chh antibody, chh-a antibody, dhh antibody, dhh-1 antibody, dhh-A antibody, hh4 antibody, x-chh antibody, desert hedgehog antibody, desert hedgehog L homeolog antibody, desert hedgehog S homeolog antibody, DHH antibody, dhh antibody, Dhh antibody, dhh.L antibody, dhh.S antibody

Target Type: Species

Background:

Background: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

Aliases: C78960 antibody, Desert hedgehog (Drosophila) homolog antibody, Desert hedgehog antibody, Desert hedgehog homolog (Drosophila) antibody, Desert hedgehog protein C-product antibody, Desert hedgehog protein precursor antibody, DHH antibody, DHH_HUMAN antibody, GDXYM antibody, HHG-3 antibody, Hira antibody, SRXY7 antibody

UniProt: O43323

Pathways: Hedgehog Signaling