MARVELD1 antibody

Catalog No. ABIN7191408

Product Details anti-MARVELD1 Antibody

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARVELD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human MARVELD1

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MARVELD1

Target: MARVELD1 (MARVEL Domain Containing 1 (MARVELD1))

Alternative Name: MARVELD1 (MARVELD1 Products)

Synonyms: Mrvldc1 antibody, AI504298 antibody, GB14 antibody, MARVD1 antibody, MRVLDC1 antibody, RP11-548K23.8 antibody, bA548K23.8 antibody, MARVEL domain containing 1 antibody, MARVEL (membrane-associating) domain containing 1 antibody, Marveld1 antibody, MARVELD1 antibody

Background:

Background: MARVELD1 (MARVEL domain containing 1), also known as GB14, MARVD1 or MRVLDC1, is a 173 amino acid protein that is widely expressed and contains one MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. The MARVEL domain, which is common in Occludin proteins, is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. Localizing to the nucleus, MARVELD1 is downregulated in primary multiple tumors of liver, bladder, ovary, vulva, breast, testis, uterus, kidney and testis. The gene encoding MARVELD1 maps to human chromosome 10, which makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome and Cowden syndrome.

Aliases: GB14 antibody, MALD1_HUMAN antibody, MARVD1 antibody, MARVEL (membrane-associating) domain containing 1 antibody, MARVEL domain containing protein 1 antibody, MARVEL domain-containing protein 1 antibody, MARVELD1 antibody, MRVLDC1 antibody, Putative MARVEL domain containing protein 1 antibody

UniProt: Q9BSK0