NKp44/NCR2 antibody

Catalog No. ABIN7191592

Product Details anti-NKp44/NCR2 Antibody

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKp44/NCR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human NCR2

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NKp44/NCR2

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Alternative Name: NCR2 (NCR2 Products)

Synonyms: CD336 antibody, LY95 antibody, NK-p44 antibody, NKP44 antibody, dJ149M18.1 antibody, uncharacterized LOC609023 antibody, natural cytotoxicity triggering receptor 2 antibody, LOC609023 antibody, NCR2 antibody

Background:

Background: Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Aliases: Activating NK receptor NKp44 antibody, CD336 antibody, CD336 antigen antibody, dJ149M18.1 antibody, LY95 antibody, Lymphocyte antigen 95 (activating NK receptor, NK p44) antibody, Lymphocyte antigen 95 homolog (activating NK receptor, NK p44) antibody, Lymphocyte antigen 95 homolog antibody, Lymphocyte antigen 95, mouse, homolog of antibody, Natural cytotoxicity triggering receptor 2 antibody, Natural killer cell p44 related protein antibody, Natural killer cell p44-related protein antibody, NCR2 antibody, NCTR2_HUMAN antibody, NK cell activating receptor (NKp44) antibody, NK cell activating receptor antibody, NK cell-activating receptor antibody, NK p44 antibody, NK-p44 antibody, NKp44 antibody

UniProt: O95944