NPPC antibody

Catalog No. ABIN7191692

Product Details anti-NPPC Antibody

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPPC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human NPPC

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:10000, IHC:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NPPC

Target: NPPC (Natriuretic Peptide Type C (NPPC))

Alternative Name: NPPC (NPPC Products)

Synonyms: CNPF antibody, CNPI antibody, CNPII antibody, Cnp1 antibody, CNP antibody, lbab antibody, CNP2 antibody, CNP3 antibody, cnp antibody, nppc antibody, 2',3'-cyclic nucleotide 3' phosphodiesterase antibody, natriuretic peptide type C antibody, natriuretic peptide C antibody, natriuretic peptide C S homeolog antibody, Cnp antibody, Nppc antibody, NPPC antibody, nppc.S antibody

Background:

Background: This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.

Aliases: ANFC_HUMAN antibody, C type natriuretic peptide precursor antibody, CNP antibody, CNP-53 antibody, CNP2 antibody, Natriuretic peptide C antibody, Natriuretic peptide precursor C antibody, NPPC antibody

UniProt: P23582