PFN2 antibody
-
- Target See all PFN2 Antibodies
- PFN2 (Profilin 2 (PFN2))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PFN2 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human PFN2
- Isotype
- IgG
- Top Product
- Discover our top product PFN2 Primary Antibody
-
-
- Application Notes
- ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- PFN2 (Profilin 2 (PFN2))
- Alternative Name
- PFN2 (PFN2 Products)
- Synonyms
- D3S1319E antibody, PFL antibody, Pfn antibody, Profilin2 antibody, XProfilin2 antibody, PFN2 antibody, PRO2 antibody, Profilin-2 antibody, pfl antibody, d3s1319e antibody, profilin-2 antibody, F17A13.170 antibody, F17A13_170 antibody, PRF2 antibody, PROFILIN antibody, PROFILIN 2 antibody, profilin 2 antibody, wu:fb01g08 antibody, wu:fb54f09 antibody, wu:fd58f06 antibody, profilin 2 antibody, profilin 2 L homeolog antibody, profilin homolog 2 antibody, Profilin-2 antibody, PFN2 antibody, Pfn2 antibody, pfn2.L antibody, prf2 antibody, pfn2 antibody, pfn-2 antibody
- Background
-
Background: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Aliases: D3S1319E antibody, PFL antibody, PFN 2 antibody, Pfn2 antibody, PROF2_HUMAN antibody, Profilin II antibody, Profilin-2 antibody, Profilin2 antibody, ProfilinII antibody
- UniProt
- P35080
- Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
-