ITGAD antibody (AA 18-172)

Catalog No. ABIN7193306

Product Details anti-ITGAD Antibody

Target: ITGAD (Integrin alpha D (ITGAD))

Binding Specificity: AA 18-172

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD11D (AA: extra 18-172) expressed in E. coli.

Clone: 3D7A6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for ITGAD

Target: ITGAD (Integrin alpha D (ITGAD))

Alternative Name: CD11D (ITGAD Products)

Synonyms: CD11d antibody, ADB2 antibody, CD11D antibody, Cd11d antibody, Itgax antibody, integrin subunit alpha D antibody, integrin, alpha D antibody, ITGAD antibody, Itgad antibody

Background:

Description: This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants.

Aliases: ITGAD, ADB2

Molecular Weight: 126.8 kDa

Gene ID: 3681

Pathways: Activated T Cell Proliferation, Integrin Complex