PIDD antibody (AA 776-910)

Catalog No. ABIN7193396

The Mouse Monoclonal anti-PIDD antibody has been validated for ELISA. It is suitable to detect PIDD in samples from Human.

Quick Overview for PIDD antibody (AA 776-910) (ABIN7193396)

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PIDD antibody is un-conjugated

Application: ELISA

Clone: 3C5G8

Product Details anti-PIDD Antibody

Binding Specificity: AA 776-910

Purpose: PIDD1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human PIDD1 (AA: 776-910) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PIDD

Target: PIDD (P53-Induced Death Domain Protein (PIDD))

Alternative Name: PIDD1

Background:

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Molecular Weight: 99.7 kDa

Gene ID: 55367

UniProt: Q9HB75

Pathways: p53 Signaling, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity