MME antibody (AA 52-246)
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- Target See all MME Antibodies
- MME (Membrane Metallo-Endopeptidase (MME))
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Binding Specificity
- AA 52-246
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MME antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD10 (AA: 52-246) expressed in E. coli.
- Clone
- 6D5F2
- Isotype
- IgG1
- Top Product
- Discover our top product MME Primary Antibody
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- Application Notes
- WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- MME (Membrane Metallo-Endopeptidase (MME))
- Alternative Name
- CD10 (MME Products)
- Synonyms
- CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
- Background
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Description: The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Aliases: MME, NEP, SFE, CALLA, CMT2T, SCA43
- Molecular Weight
- 85.5 kDa
- Gene ID
- 4311
- Pathways
- RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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