EPH Receptor B6 antibody (AA 830-910)

Catalog No. ABIN7214766

The Rabbit Polyclonal anti-EPH Receptor B6 antibody (ABIN7214766) specifically detects EPH Receptor B6 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EPH Receptor B6 antibody (AA 830-910) (ABIN7214766)

Target: EPH Receptor B6 (EPHB6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-EPH Receptor B6 Antibody

Binding Specificity: AA 830-910

Purpose: Rabbit Anti-EphB6 Polyclonal Antibody

Specificity: EphB6 Polyclonal Antibody detects endogenous levels of EphB6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human EphB6 at AA range: 830-910

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Alternative Name: EphB6

Background: EPHB6, Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6EPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein (EPH receptor B6) does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 119kD

Gene ID: 2051

UniProt: O15197

Pathways: RTK Signaling, Hormone Transport