Neurofibromin 1 antibody (AA 30-110)

Catalog No. ABIN7222718

The Rabbit Polyclonal anti-Neurofibromin 1 antibody is suitable to detect Neurofibromin 1 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IF and IHC.

Quick Overview for Neurofibromin 1 antibody (AA 30-110) (ABIN7222718)

Target: Neurofibromin 1 (NF1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurofibromin 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-Neurofibromin 1 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-NF-1 Polyclonal Antibody

Specificity: NF-1 Polyclonal Antibody detects endogenous levels of NF-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human NF-1 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Neurofibromin 1

Target: Neurofibromin 1 (NF1)

Alternative Name: NF-1

Background: NFIA, KIAA1439, Nuclear factor 1 A-type, NF1-A, Nuclear factor 1/A, CCAAT-box-binding transcription factor, CTF, Nuclear factor I/A, NF-I/A, NFI-A, TGGCA-binding protein, NFIB, Nuclear factor 1 B-type, NF1-B, Nuclear factor 1/B, CCAAT-box-bNFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 55kD

Gene ID: 4774, 4781, 4782

UniProt: Q12857, O00712, P08651, Q14938

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity