UCP1 antibody

Catalog No. ABIN7232024

Product Details anti-UCP1 Antibody

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: UCP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UCP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UCP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for UCP1

Target: UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))

Alternative Name: UCP1 (UCP1 Products)

Synonyms: ARABIDOPSIS THALIANA PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 1 antibody, ARABIDOPSIS THALIANA UNCOUPLING PROTEIN 1 antibody, ATPUMP1 antibody, ATUCP1 antibody, UCP antibody, UCP1 antibody, UNCOUPLING PROTEIN 1 antibody, plant uncoupling mitochondrial protein 1 antibody, ucp antibody, slc25a7 antibody, SLC25A7 antibody, AI385626 antibody, Slc25a7 antibody, Ucp antibody, Ucpa antibody, Uncp antibody, plant uncoupling mitochondrial protein 1 antibody, uncoupling protein 1 antibody, uncoupling protein 1 L homeolog antibody, uncoupling protein 1 (mitochondrial, proton carrier) antibody, PUMP1 antibody, UCP1 antibody, ucp1.L antibody, ucp1 antibody, Ucp1 antibody

Background: Rabbit Anti-UCP1 Polyclonal Antibody,Mitochondrial brown fat uncoupling protein 1, UCP 1, Solute carrier family 25 member 7, Thermogenin,Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.,UCP1

Molecular Weight: observerd band 33kDa

Gene ID: 7350

UniProt: P25874

Pathways: Proton Transport, Brown Fat Cell Differentiation