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Histone H2A antibody (C-Term)
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Histone H2A Antibody
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Target
See all Histone H2A Antibodies
Histone H2A
Binding Specificity
All epitopes for Histone H2A antibodies
C-Term
Reactivity
All reactivities for Histone H2A antibodies
Human
Host
All hosts for Histone H2A antibodies
Rabbit
Clonality
All clonalities for Histone H2A antibodies
Polyclonal
Conjugate
All conjugates for Histone H2A antibodies
This Histone H2A antibody is un-conjugated
Application
All applications for Histone H2A antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purpose
Histone H2AX Rabbit pAb
Sequence
VYLAAVLEYL TAEILELAGN AARDNKKTRI IPRHLQLAIR NDEELNKLLG GVTIAQGGVL PNIQAVLLPK KTSATVGPKA PSGGKKATQA SQEY
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human Histone H2AX (NP_002096.1).
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Histone H2A
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Target
Histone H2A
Abstract
Histone H2A Products
Synonyms
5499 antibody, CG5499 antibody, Dmel\\CG5499 antibody, H2A antibody, H2A.F/Z antibody, H2A.X antibody, H2A.Z antibody, H2AV antibody, H2AV_DROM antibody, H2AX antibody, H2AZ antibody, H2Av antibody, H2AvD antibody, H2a.V antibody, H2av antibody, H2avD antibody, HIS antibody, HIS2AV antibody, HIS2AVD antibody, His antibody, His2 antibody, His2AV antibody, His2AvD antibody, HisH2Av antibody, Hist antibody, Hist2av antibody, gamma-H2Av antibody, gamma-HIS2AV antibody, gamma-His2Av antibody, gammaH2Av antibody, h2AvD antibody, his antibody, l(3)05146 antibody, l(3)810 antibody, l(3)97Dd antibody, l(3)L1602 antibody, DDBDRAFT_0205974 antibody, DDBDRAFT_0216271 antibody, DDB_0205974 antibody, DDB_0216271 antibody, RGD1564767 antibody, H2a-221 antibody, H2A-III antibody, HIST1H2AA antibody, Histone H2A variant antibody, putative histone H2A antibody, histone H2A antibody, histone cluster 1 H2A family member F antibody, histone H2A-like antibody, histone cluster 1, H2af antibody, histone2A1 antibody, histone cluster 1, H2A, III antibody, histone cluster 1, H2ac antibody, His2Av antibody, LMJF_17_0280 antibody, H2AX antibody, Hist1h2af antibody, LOC100425378 antibody, his2a1 antibody, HIST1H2A3 antibody, HIST1H2AC antibody, h2a-A antibody
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.,H2A.X,H2A/X,H2AX,Histone H2AX,H2AFX,histone H2AX,gamma H2A.X,γH2AX,Epigenetics & Nuclear Signaling,Histones,DNA Damage & Repair,Histone H2A
Molecular Weight
15kDa
Gene ID
3014
UniProt
P16104
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