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OPN4 antibody (AA 365-489)

OPN4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7269103
  • Target See all OPN4 Antibodies
    OPN4 (Opsin 4 (OPN4))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 365-489
    Reactivity
    • 7
    • 1
    • 1
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 7
    This OPN4 antibody is un-conjugated
    Application
    • 7
    • 6
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purpose
    OPN4 Rabbit pAb
    Sequence
    HPKYRVAIAQ HLPCLGVLLG VSRRHSRPYP SYRSTHRSTL TSHTSNLSWI SIRRRQESLG SESEVGWTHM EAAAVWGAAQ QANGRSLYGQ GLEDLEAKAP PRPQGHEAET PGKTKGLIPS QDPRM
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 365-489 of human OPN4 (NP_001025186.1).
    Isotype
    IgG
    Top Product
    Discover our top product OPN4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    OPN4 (Opsin 4 (OPN4))
    Alternative Name
    OPN4 (OPN4 Products)
    Synonyms
    MOP antibody, 1110007J02Rik antibody, Gm533 antibody, OPN4-2 antibody, cOpn4L antibody, melanopsin antibody, opn4-A antibody, Xmop antibody, opn4 antibody, opn4d antibody, opsin 4 antibody, opsin 4 (melanopsin) antibody, melanopsin antibody, melanopsin-B-like L homeolog antibody, opsin 4a (melanopsin) antibody, OPN4 antibody, Opn4 antibody, LOC100303707 antibody, LOC100485437.L antibody, opn4a antibody
    Background
    Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,OPN4,MOP,opsin 4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,OPN4
    Molecular Weight
    52kDa/53kDa
    Gene ID
    94233
    UniProt
    Q9UHM6
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