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PVRL2 antibody
PVRL2
Reactivity: Human
WB, IHC
Host: Rabbit
Monoclonal
unconjugated
Product Details anti-PVRL2 Antibody
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Target
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PVRL2
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
Reactivity
All reactivities for PVRL2 antibodies
Human
Host
All hosts for PVRL2 antibodies
Rabbit
Clonality
All clonalities for PVRL2 antibodies
Monoclonal
Conjugate
All conjugates for PVRL2 antibodies
This PVRL2 antibody is un-conjugated
Application
All applications for PVRL2 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Purpose
Nectin 2/CD112 Rabbit mAb
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Monoclonal Antibodies
Purification
Affinity purification
Immunogen
A synthesized peptide derived from human Nectin 2/CD112
Isotype
IgG
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Discover our top product PVRL2 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PVRL2
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Target
PVRL2
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
Alternative Name
NECTIN2 (PVRL2 Products )
Synonyms
prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody
Background
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],CD112, HVEB, PRR2, PVRL2, PVRR2,CDs,Immunology & Inflammation,NECTIN2
Molecular Weight
62-75kDa
Gene ID
5819
UniProt
Q92692
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cell-Cell Junction Organization
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