RGS17 antibody (AA 45-130)

Catalog No. ABIN7269896

The Rabbit Polyclonal anti-RGS17 antibody has been validated for WB. It is suitable to detect RGS17 in samples from Human.

Quick Overview for RGS17 antibody (AA 45-130) (ABIN7269896)

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS17 Antibody

Binding Specificity: AA 45-130

Purpose: RGS17 Rabbit pAb

Sequence: NEERGENAGR PTHTTKMESI QVLEECQNPT AEEVLSWSQN FDKMMKAPAG RNLFREFLRT EYSEENLLFW LACEDLKKEQ NKKVIE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 45-130 of human RGS17 (NP_036551.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Alternative Name: RGS17

Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.,RGS17,RGS-17,RGSZ2,hRGS17,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,RGS17

Molecular Weight: 24kDa

Gene ID: 26575

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling