RGS17 antibody (Regulator of G-Protein Signaling 17) (AA 148-160) Primary Antibody
RGS17 Reactivity: Human IF, WB Host: Rabbit Polyclonal
Catalog No. ABIN784001
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- Binding Specificity
- AA 148-160
- This RGS17 antibody is un-conjugated
- Immunofluorescence (IF), Western Blotting (WB)
- Recognizes RGS17.
Cellular Localization: Membrane, Lipid-anchor, Nucleus, Cytoplasm.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Antigen-Affinity Chromatography.
- Synthetic peptide contain a sequence corresponding to a region within amino acids 148 and 160 of Human RGS17.
- Application Notes
- Optimal working dilution should be determined by the investigator.
- For Research Use only
- 1.0 mg/mL
- 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- -20 °C
- Storage Comment
- Store the antibody undiluted (in aliquots) at -20 °C.
- Alternative Name
- RGS17 (RGS17 Antibody Abstract)
- This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Synonyms: RGS-17, RGSZ2, Regulator of G-protein signaling 17
- Gene ID
- 26575, 9606
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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