STAT1 antibody

Catalog No. ABIN7270303

This Rabbit Monoclonal antibody specifically detects STAT1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for STAT1 antibody (ABIN7270303)

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STAT1 Antibody

Purpose: STAT1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human STAT1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STAT1

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Alternative Name: STAT1

Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91,STAT1 alpha,STAT1,Apoptosis,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Protein phosphorylation,Signal Transduction,Transcription Factors,STAT1

Molecular Weight: 87kDa

Gene ID: 6772

UniProt: P42224

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events