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FCER2 antibody

GMP Grade FCER2 Reactivity: Human FACS Host: Mouse Monoclonal HD50 unconjugated
Catalog No. ABIN7271885
  • Target See all FCER2 Antibodies
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Reactivity
    • 101
    • 52
    • 10
    Human
    Host
    • 56
    • 51
    • 19
    Mouse
    Clonality
    • 77
    • 47
    • 2
    Monoclonal
    Conjugate
    • 58
    • 14
    • 10
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCER2 antibody is un-conjugated
    Application
    • 72
    • 51
    • 36
    • 20
    • 15
    • 11
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    CD23 Unconjugated Antibody
    Characteristics
    The clone HD50 is a mouse monoclonal antibody selectively binds with the 45 kD type II integral membrane glycoprotein having a low-affinity receptor for immunoglobulin (Ig)E commonly known as CD23 or FcεRII. CD23 is the only FcR which does not belong to the immunoglobulin gene superfamily and is expressed on mature B cells, monocytes, eosinophils, platelets and dendritic cells. Similar to the most FcR, soluble forms of CD23 (sCD23) are released into extracellular fluids. CD23 interacts with CD21, CD11b and CD11c indicates that CD23 should be viewed not only as a low affinity IgE receptor but also as an adhesion molecule involved in cell-cell interaction. Presence of cell surface and soluble CD23 in serum is considered as one of the prognostic markers of chronic lymphocytic leukemia (CLL).
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Extracytoplasmic part of CD23 antigen on B lymphocytes and monocytes
    Clone
    HD50
    Isotype
    IgG2b, kappa
    Top Product
    Discover our top product FCER2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Alternative Name
    CD23 (FCER2 Products)
    Synonyms
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    Gene ID
    2208
    UniProt
    P06734
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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