The clone 32.2, a mouse monoclonal antibody selectively binds with a 72kD single chain type I glycoprotein known as CD64 or FcγRI. CD64 is a member of the immunoglobulin superfamily. FcγRI is expressed on the cell surface in association with the γ-chain. Expression of CD64 is observed on monocytes/macrophages, dendritic cells, and activated granulocytes. CD64 plays important role in the process of antigen capture, phagocytosis and antibody-dependent cellular cytotoxicity (ADCC).
Purification
Purified
Purity
>95 %
Grade
GMP Grade
Immunogen
Partially purified detergent lysate of the high affinity Fc receptor from U937 cells