DENND4C antibody (Atto 488)

Catalog No. ABIN7272061

Product Details anti-DENND4C Antibody (Atto 488)

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DENND4C antibody is conjugated to Atto 488

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purpose: Mouse Anti-Human DENND4C Monoclonal IgG1,

Specificity: Widely expressed,Detects ~213 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Full Length Human Recombinant Dennd4c protein

Clone: 3E8

Isotype: IgG1

Application Details

Application Notes: WB (1:1000), optimal dilutions for assays should be determined by the user.

Comment:

A 1:1000 dilution was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Conjugated antibodies should be stored at 4°C

Target Details for DENND4C

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Alternative Name: DENND4C (DENND4C Products)

Synonyms: 1700065A05Rik antibody, AA420392 antibody, C9orf55 antibody, C9orf55B antibody, bA513M16.3 antibody, DENN domain containing 4C antibody, DENN/MADD domain containing 4C antibody, DENND4C antibody, Dennd4c antibody

Background: Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3)., cellular localisation: Cell membrane , Cytoplasm , Cytoplasmic vesicle , Membrane

Gene ID: 55667

NCBI Accession: NM_017925

UniProt: Q5VZ89