RENT1/UPF1 antibody

Catalog No. ABIN7384488

Product Details anti-RENT1/UPF1 Antibody

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RENT1/UPF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity Purified

Clone: R02-2E6

Isotype: IgG

Application Details

Application Notes: WB 1:2000-1:3000 IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RENT1/UPF1

Target: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Alternative Name: RENT1 (UPF1 Products)

Synonyms: HUPF1 antibody, NORF1 antibody, RENT1 antibody, pNORF1 antibody, smg-2 antibody, B430202H16Rik antibody, PNORF-1 antibody, Rent1 antibody, Upflp antibody, rent1 antibody, wu:fi40f07 antibody, wu:fj48a01 antibody, zgc:55472 antibody, Tb05.3C6.50 antibody, AO090012000584 antibody, hupf1 antibody, norf1 antibody, pnorf1 antibody, upf1 antibody, UPF1, RNA helicase and ATPase antibody, UPF1 regulator of nonsense transcripts homolog (yeast) antibody, upf1 regulator of nonsense transcripts homolog (yeast) antibody, regulator of nonsense transcripts 1 antibody, Regulator of nonsense transcripts 1 antibody, UPF1 regulator of nonsense transcripts homolog S homeolog antibody, UPF1 antibody, Upf1 antibody, upf1 antibody, Tc00.1047053511317.30 antibody, Tb927.5.2140 antibody, TVAG_453890 antibody, TVAG_237840 antibody, AOR_1_1018194 antibody, HPB8_739 antibody, smg-2 antibody, upf1.S antibody

Background: ATP dependent helicase RENT1,ATP-dependent helicase RENT1,Delta helicase,FLJ43809,FLJ46894,HUPF 1,hUpf1,KIAA0221,Nonsense mRNA reducing factor 1,NORF 1,NORF1,pNORF 1,pNORF1,Regulator of nonsense transcripts 1,RENT 1,RENT1,RENT1,Smg 2,Smg 2 homolog nonsense mediated mRNA decay factor,UP Frameshift 1,Up frameshift mutation 1 homolog (S. cerevisiae),Up frameshift mutation 1 homolog,Up frameshift suppressor 1 homolog,Up-frameshift suppressor 1 homolog,UPF 1,UPF 1 regulator of nonsense transcripts homolog,upf1,UPF1 regulator of nonsense transcripts homolog,UPF1 RNA helicase and ATPase,Yeast Upf1p homolog,This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. 

Molecular Weight:

Observed_MW: 124kDa

Calculated_MW: 124kDa

Gene ID: 5976

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interactome