BCKDHA antibody (AA 395-445)

Catalog No. ABIN7449870

Product Details anti-BCKDHA Antibody

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Binding Specificity: AA 395-445

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCKDHA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-BCKDHA Antibody, Affinity Purified

Predicted Reactivity: Rat,Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 395 and 445

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BCKDHA

Target: BCKDHA (Branched Chain Keto Acid Dehydrogenase E1, alpha Polypeptide (BCKDHA))

Alternative Name: BCKDHA (BCKDHA Products)

Synonyms: wu:fd20d04 antibody, zgc:110049 antibody, BCKDE1A antibody, MSU antibody, MSUD1 antibody, OVD1A antibody, BCKDA antibody, E1a antibody, 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial antibody, branched chain keto acid dehydrogenase E1, alpha polypeptide antibody, 2-oxoisovalerate dehydrogenase alpha subunit (branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) antibody, branched chain ketoacid dehydrogenase E1, alpha polypeptide antibody, LOC704978 antibody, bckdha antibody, BCKDHA antibody, BckdhA antibody, Bckdha antibody

Background: Background: BCKDHA (branched chain keto acid dehydrogenase E1, alpha polypeptide) is a component of the branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex. The BCKD complex is an inner mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). Mutations in this gene result in maple syrup urine disease, type IA [taken from NCBI Entrez Gene (Gene ID: 593)].

Gene ID: 593

NCBI Accession: NP_000700

UniProt: P12694