PSMD13 antibody (AA 1-50)

Catalog No. ABIN7450609

Product Details anti-PSMD13 Antibody

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-PSMD13 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMD13

Target: PSMD13 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13))

Alternative Name: PSMD13 (PSMD13 Products)

Synonyms: HSPC027 antibody, Rpn9 antibody, S11 antibody, p40.5 antibody, zgc:56377 antibody, zgc:77482 antibody, MGC84231 antibody, MGC69415 antibody, DDBDRAFT_0186342 antibody, DDBDRAFT_0233004 antibody, DDB_0186342 antibody, DDB_0233004 antibody, proteasome 26S subunit, non-ATPase 13 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 antibody, proteasome 26S subunit, non-ATPase 13 S homeolog antibody, 26S proteasome non-ATPase regulatory subunit 13 antibody, PSMD13 antibody, Psmd13 antibody, psmd13 antibody, psmd13.S antibody, psmD13 antibody

Background: Background: Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD13 is a non-ATPase subunit of the 19S regulator. [taken from NCBI Entrez Gene (Gene ID: 5719)].

Gene ID: 5719

NCBI Accession: NP_002808

UniProt: Q9UNM6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway