IKK alpha antibody (AA 550-600)

Catalog No. ABIN7452349

This Rabbit Polyclonal antibody specifically detects IKK alpha in IP. It exhibits reactivity toward Human.

Quick Overview for IKK alpha antibody (AA 550-600) (ABIN7452349)

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK alpha antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-IKK alpha Antibody

Binding Specificity: AA 550-600

Purpose: Rabbit anti-IKK-alpha Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: between AA 550 and 600

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-IKK-alpha antibody A301-933A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IKK alpha

Target: IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))

Alternative Name: IKK-alpha

Background: Background: I kappa-B kinase-alpha (IKK-alpha) is part of the IKK complex composed of two regulatory subunits, IKK-alpha and IKK-beta, and a regulatory subunit, IKK-gamma/NEMO. The IKK complex functions to phosphorylate and inactivate I kappa B, an inhibitor of the NF-kappa B transcription factor.

Gene ID: 1147

NCBI Accession: NP_001269

UniProt: O15111

Pathways: PI3K-Akt Signaling, NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins