Recombinant FOXO3 antibody (AA 450-500)

Catalog No. ABIN7452580

This Rabbit Monoclonal antibody specifically detects FOXO3 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant FOXO3 antibody (AA 450-500) (ABIN7452580)

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FOXO3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: BLR140H

Product Details anti-FOXO3 Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-FOXO3a Recombinant Monoclonal Antibody [BLR140H]

Immunogen: between AA 450 and 500

Isotype: IgG

Application Details

Application Notes:

IP: 20 μL/1 mg lysate

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 40 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXO3

Target: FOXO3 (Forkhead Box O3 (FOXO3))

Alternative Name: FOXO3a

Background: Background: Forkhead box protein 03A (FOXO3a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO3a is a transcription factor that functions to induce apoptosis in the absence of survival factors and in response to oxidative stress. Under conditions of oxidative stress FOXO3a is acetylated and localized to the nucleus where it may act as a transcriptional repressor.

Gene ID: 2309

NCBI Accession: NP_001446

UniProt: O43524

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis