PSMB1 antibody
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- Target See all PSMB1 Antibodies
- PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMB1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human PSMB1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product PSMB1 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: 293T , A431
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.89 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
- Alternative Name
- proteasome subunit beta 1 (PSMB1 Products)
- Synonyms
- DDBDRAFT_0217063 antibody, DDBDRAFT_0232957 antibody, DDB_0217063 antibody, DDB_0232957 antibody, AA409053 antibody, C81484 antibody, Lmpc5 antibody, HC5 antibody, PMSB1 antibody, PSC5 antibody, wu:fc51f06 antibody, zgc:103665 antibody, proteasome subunit beta 1 antibody, 20S proteasome subunit beta-1 antibody, proteasome subunit beta type 1 antibody, proteasome (prosome, macropain) subunit, beta type 1 antibody, proteasome subunit beta 1 S homeolog antibody, psmb1 antibody, PSMB1 antibody, psmB1 antibody, LOC100286342 antibody, Psmb1 antibody, psmb1.S antibody
- Background
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Synonyms: proteasome subunit beta 1 , HC5 , PMSB1 , PSC5
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq]
- Molecular Weight
- 26 kDa
- Gene ID
- 5689
- UniProt
- P20618
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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