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SIGLEC10 antibody (Extracellular Domain)

SIGLEC10 Reactivity: Human ELISA, IHC, IP Host: Mouse Monoclonal 5G6 unconjugated
Catalog No. ABIN7506216
  • Target See all SIGLEC10 Antibodies
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    Binding Specificity
    • 15
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivity
    • 57
    • 20
    • 6
    • 5
    • 4
    Human
    Host
    • 48
    • 9
    • 1
    Mouse
    Clonality
    • 49
    • 9
    Monoclonal
    Conjugate
    • 17
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC10 antibody is un-conjugated
    Application
    • 48
    • 27
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purpose
    Anti-Hu SIGLEC10 Purified
    Specificity
    The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogen
    SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
    Clone
    5G6
    Isotype
    IgG1
    Top Product
    Discover our top product SIGLEC10 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    Alternative Name
    SIGLEC10 (SIGLEC10 Products)
    Synonyms
    PRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like lectin 10 antibody, sialic acid binding Ig-like lectin 10 antibody, sialic acid-binding Ig-like lectin 10 antibody, SIGLEC10 antibody, Siglec10 antibody, LOC484343 antibody, LOC100066644 antibody, siglec10 antibody, LOC100513863 antibody, LOC100340374 antibody
    Background
    Sialic acid binding Ig like lectin 10,SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.,PRO940, SGL2
    Gene ID
    89790
    UniProt
    Q96LC7
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