This IL-6R (Tocilizumab Biosimilar) antibody is un-conjugated
Application
Immunofluorescence (IF)
Purpose
Humanized recombinant monoclonal antibody raised against human IL-6.
Specificity
Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
Cross-Reactivity
Human
Immunogen
Original antibody is raised against by CDR grafting of mouse PM-1 antibody onto human REI and NEW framework regions to create rhPM-1.