GTPase NRas antibody

Catalog No. ABIN7606143

This Rabbit Monoclonal antibody specifically detects GTPase NRas in WB, FACS and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GTPase NRas antibody (ABIN7606143)

Target: GTPase NRas (NRAS)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GTPase NRas antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: DBC-14

Product Details anti-GTPase NRas Antibody

Purpose: Anti-Ras NRAS Rabbit Monoclonal Antibody

Characteristics: Anti-Ras NRAS Rabbit Monoclonal Antibody (ABIN7606143). Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human Ras

Isotype: IgG

Application Details

Application Notes: WB 1:10000-1:20000
IP 1:20
FC 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Target Details for GTPase NRas

Target: GTPase NRas (NRAS)

Alternative Name: NRAS

Background:

Synonyms: GTPase NRas,Transforming protein N-Ras,NRAS,HRAS1,

Tissue Specificity: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. .

Molecular Weight: 21 kDa

Pathways: p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling